Cerebral Hemodynamic Changes in Stroke During Sleep-Disordered Breathing

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Cerebral hemodynamic changes in stroke during sleep-disordered breathing.

BACKGROUND AND PURPOSE Sleep-disordered breathing (SDB) negatively impacts stroke outcome. Near-infrared spectroscopy showed the acute cerebral hemodynamic effects of SDB. METHODS Eleven patients (7 men, age 61±13 years) with acute/subacute middle cerebral artery stroke (National Institutes of Health Stroke Scale score 10±7) and SDB (apnea-hypopnea index 32±28/hour) were assessed with nocturn...

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Sleep-disordered breathing is common after stroke and most often presents as obstructive sleep apnea (OSA), with an estimated prevalence between 43% and 70% compared with 4% and 24% in the general population. OSA is the result of partial or complete closure of the upper airway while attempting to breathe during sleep. It is characterized by snoring, hypopnea, and apnea with intermittent awakeni...

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Sleep-related breathing disorders are strongly associated with increased risk of stroke independent of known risk factors. The direction of causation favors sleep-disordered breathing leading to stroke rather than the other way around, although definitive proof of this awaits the results of prospective cohort studies. If causal, even a moderately elevated risk of stroke coupled with the high pr...

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ژورنال

عنوان ژورنال: Stroke

سال: 2012

ISSN: 0039-2499,1524-4628

DOI: 10.1161/strokeaha.112.656298